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Utrogestan is a drug of progesterone. It is used for conditions related to progesterone deficiency, including premenstrual syndrome, dysmenorrhea (menstrual irregularities), fibrocystic breast, premenopausal syndrome and menopause (with estrogens).
The drug is manufactured by Laboratoires Besins International.

| Quantity | per Pack | per Item | You save | Add to Cart |
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30 Capsules |
$ 38.95 | $ 1.30 | - | |
|
90 Capsules |
$ 99.95 | $ 1.11 | $ 16.90 | |
|
180 Capsules |
$ 189.95 | $ 1.06 | $ 43.75 |
| Quantity | per Pack | per Item | You save | Add to Cart |
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14 Capsules |
$ 38.95 | $ 2.78 | - | |
|
42 Capsules |
$ 99.95 | $ 2.38 | $ 16.90 | |
|
84 Capsules |
$ 189.95 | $ 2.26 | $ 43.75 |
- Product Description
- Side Effects
- Safety Information
Drug name: Utrogestan (progesterone)
Therapeutic effects: Progesterone, the active ingredient of Utrogestan, is a hormone of the yellow body. It promotes formation of a normal secretory endometrium in women, causes the endometrium to move from proliferative phase to secretory phase, and after fertilization promotes its transition to a state necessary for the development of a fertilized egg. Utrogestan reduces the excitability and contractility of muscles of the uterus and fallopian tubes, stimulates the development of terminal elements of the breast. It has anti-androgenic activity due to regulation of the active metabolite ( dihydrotestosterone) production, increases urine output due to anti-aldosterone effect.
Indications:
For oral use:
- Endocrine infertility (due to luteal insufficiency)
- Prevention of recurrent miscarriage or threat of miscarriage in the background of luteal insufficiency
- Threatened premature delivery
- Premenstrual syndrome
- Irregular menstruation (dysmenorrhea, oligo- and amenorrhea, dysfunctional uterine bleeding, etc.)
- Fibrocystic mastopathy, mastalgia
- Premenopause, menopause, postmenopause - hormone replacement therapy in combination with estrogen agents
Intravaginal use:
- Hormone replacement therapy in case of progesterone deficiency in non-functional / missing ovaries (in egg cells donation)
- Support of the luteal phase in preparation for extracorporeal fertilization
- Support of the luteal phase in spontaneous or induced menstrual cycle
- Premature menopause
- Premenopause, menopause, postmenopause - hormone replacement therapy in combination with estrogen agents
- Endocrine sterility
- Prevention of habitual or threatened miscarriage due to luteal insufficiency
- Prevention of uterine fibroids
- Prevention of endometriosis
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Side effects are usually observed when taking Utrogestan orally:
- from the nervous system: drowsiness, transient dizziness
- from the reproductive system: shortening of menstrual cycle, intermenstrual spotting / bleeding (rare)
- other: cholestatic jaundice, itching, allergic reactions
Drug interactions:
Utrogestan may interact with the following groups of drugs:
- liver enzymes inducers
- antibiotics
- diuretics
- antihypertensive drugs
- immunosuppressants
- anticoagulants
- oxytocin
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Cautions and restrictions:
Utrogestan should not be used in the following cases:
- Hypersensitivity to any component of the drug
- Vaginal bleeding of unknown etiology
- Incomplete abortion (miscarriage)
- Porphyria
- Malignant neoplasms of breast or genitals (or suspicion on those)
Additionally for oral use:
- Tendency to thrombosis
- Acute phlebitis or thrombosis
- Severe liver disease, liver failure
With caution:
- Cardiovascular system disorders
- Arterial hypertension
- Chronic renal failure
- Diabetes mellitus
- Asthma
- Epilepsy
- Migraine
- Depression
- Hyperlipoproteinemia
- III trimester of pregnancy, breastfeeding
Additional information:
Keep the drug out of reach of children at a temperature below 25 ° C.
Shelf life: 3 years.
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