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Guttalax is a known laxative stimulant, which as the active ingredient contains Sodium picosulfate. The drug decreases absorption of electrolytes and water, thus improving intestinal peristalsis, and causing the laxative effect. The active ingredient of the drug directly stimulates intestinal receptors, thus increasing the speed of peristalsis.

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- Product Description
- Side Effects
- Safety Information
Drug name: Guttalax (Sodium picosulfate)
Therapeutic effects: The preparation is a Laxative stimulant. The effects of Guttalax are developed in the larger intestines. The sulfate radical is detaches from the molecule due to the effects of the sulfate producing microorganisms, transforming the drug into its active form diphenol. The preparation stimulates the receptors of the larger intestines, increasing their peristalsis. The effects of the drug may be monitored within 6 to 12 hours after administration.
The drug is not absorbed in the gastrointestinal tract. The active ingredient of the drug diphenol is found in trace concentrations in blood of the treated patients.
Indications: Guttalax is indicated in treatment of different constipation types including:
- Atonic constipation
- Spastic constipation
Especially constipation caused by diet, pregnancy, excessive weight, immobility and etc.
The preparation may also be used in treatment of patients with hemorrhoids or anal fissures in post-surgical period.
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As any other drug Guttalax may express several side-effects, which are severely expressed in long-term use:
- Water-electrolyte balance Potassium loss, as well as other electrolytes
- Gastrointestinal tract: dyspepsia, diarrhea, abdominal pain
- Dehydration
- Decrease of arterial pressure
In short-term use of the drug side-effects are encountered rarely.
Drug interactions: The drug should not be used together with the following groups of drugs:
- Diuretics
- Corticosteroids
- Cardiac glycosides
- Broad spectrum antibiotics
Tell your doctor about all the preparations you are currently taking before starting treatment with Guttalax, including supplements and vitamins.
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Cautions and restrictions:
- The drug should not be used in the following conditions:
- Intestinal obstruction
- Acute inflammatory disease of the GI tract
- Abdominal pain of unknown genesis
- GI tract bleeding
- Severe dehydration
- Cystitis
- I trimester of pregnancy
- Hypersensitivity to the drug or any other components of the preparation
- Constricted hernia
Guttalax should not be taken on the daily basis for long periods of time due to possible severe side-effects.
Additional information: The drug should be kept at temperatures not exceeding 25°C. Keep away from children. The length of shelf life is 5 years.
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