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Lisinopril is a commonly used ACE inhibitor. The drug is normally prescribed in treatment of arterial hypertension, however also finds its uses in chronic heart failure and Diabetic nephropathy. The preparation must not be used without an approval from your cardiologist.
The preparation is manufactured by Gedeon Richter.

| Quantity | per Pack | per Item | You save | Add to Cart |
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28 Tablets |
$ 17.95 | $ 0.64 | - | |
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56 Tablets |
$ 29.95 | $ 0.53 | $ 5.95 | |
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112 Tablets |
$ 54.95 | $ 0.49 | $ 16.85 |
| Quantity | per Pack | per Item | You save | Add to Cart |
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28 Tablets |
$ 27.95 | $ 1.00 | - | |
|
56 Tablets |
$ 49.95 | $ 0.89 | $ 5.95 | |
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112 Tablets |
$ 89.95 | $ 0.80 | $ 21.85 |
- Product Description
- Side Effects
- Safety Information
Drug name: Diroton (Lisinopril)
Therapeutic effects: Lisinopril belongs to a group of drugs called ACE inhibitors, which decrease the formation of angiotensin I and II in the human organism. The decrease in angiotensin II leads to a decrease in aldosterone release. Decreases the degradation of bradykinin and increases synthesis of prostoglandins, decreases overall peripheral resistance, arterial pressure, preload, blood pressure in the lung capillaries, increases tolerability of myocardium to stress in patients with chronic heart failure. Dilates arteries in a greater extent compared to veins.
The drug starts to work within an hour after administration. The maximum effect is reached in 6 to 7 hours. The primary effects in treatment of arterial hypertension are seen in 2-3 days of consecutive administration, stable effect is developed within 1 to 2 months of use.
Indications:
The drug is administered in treatment of:
- Arterial hypertension
- Chronic heart failure
- The drug is also used as subsidiary treatment in acute myocardial infraction
- Diabetic nephropathy.
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The preparation may exert the following side-effects:
- Cardiovascular system: hypotension, arrhythmia, chest pain, orthostatic hypotension, tachycardia
- CNS: dizziness, headache, fatiguability, somnolence, asthenia, lability, confusion
- Gastrointestinal tract: nausea, dyspepsia, decreased appetite, change of taste, abdominal pain, diarrhea, xerostomia
- Hematopoietic system: leukopenia, thrombocytopenia, neutropenia, agranulocytosis, anemia
- Allergic reaction: angioneurotic shock, rash, itching
- Other: dry cough, decrease libido, acute renal failure, arthralgia, mialgia, fever, swelling
Drug interactions: The preparation should interact with the following:
- Li+ containing drugs
- NSAID's
- Oral contraceptives
- Adrenostimulators
- Diuretics
- Ca2+ channel blockers
- Antacids
- Myelotoxic drugs
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Cautions and restrictions:
The drug should not be used in cases of:
- Known hypersensitivity to lisinopril or other ACE inhibitors
- Pregnancy
- Lactation period
Diroton should be used with caution in:
- Angioneurotic shock
- Aortic stenosis
- Cerebrovascular disease
- Coronary failure
- Ischemic heart disease
- Renal failure
- Conditions accompanied by a decrease in overall blood volume
- Elderly age
- Age prior to 18 years
Additional information:
The drug should be kept in dry conditions, at temperatures not exceeding 25C.
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